11/07/2025
Some interesting information on how to reduce oxidative expression at the cellular level. This leads to inflammation. Inflammation is the cause of all disease.
Healthy cells make energy using oxygen inside the mitochondria — this process is called oxidative phosphorylation. It’s clean, efficient, and produces about 36 ATP (energy molecules) per glucose molecule. It’s how your body was designed to function in a high-oxygen, high-voltage environment.
But when oxygen is scarce, blocked, or not utilized properly, or when mitochondria are damaged by toxins, radiation, or chronic stress, cells shift into a primitive survival mode:
They start fermenting glucose instead — a backup method called anaerobic glycolysis. This process only makes 2 ATP per glucose… but cancer cells prefer it because it’s fast, supports their rapid division, and doesn’t require mitochondria. In other words — they bypass oxygen and operate like metabolic parasites.
Root threats that push cells into this shift include:
• Low oxygen delivery to tissues
• Toxin overload (mold, pesticides, heavy metals, plastics, chemotherapy residues)
• Chronic inflammation (from gut dysbiosis, infection, trauma, or autoimmune terrain, seed oils, high sugar)
• Mitochondrial damage (EMFs, viral DNA, ROS)
• Poor blood flow, fascia tension, or stagnant lymph
• Nutrient deficiencies (magnesium, B vitamins, copper, CoQ10)
This terrain adaptation is known as the Warburg Effect — named after Nobel Prize-winning scientist Otto Warburg. It’s not just faulty DNA. It’s faulty metabolism — and the terrain, not the gene, drives the behavior.
What causes low oxygen debt which ultimately leads to inflammation and inflammation is the root of all disease?
𝐏𝐨𝐨𝐫 𝐂𝐢𝐫𝐜𝐮𝐥𝐚𝐭𝐢𝐨𝐧• Thick, sticky blood, dehydration, high fibrin levels, or low nitric oxide = oxygen can’t get where it needs to go.
𝐀𝐧𝐞𝐦𝐢𝐚 𝐨𝐫 𝐈𝐫𝐨𝐧 𝐈𝐦𝐛𝐚𝐥𝐚𝐧𝐜𝐞 • Too little iron = low oxygen-carrying hemoglobin
• Too much = oxidative stress that damages mitochondria
• Copper deficiency can block iron utilization
𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐈𝐧𝐣𝐮𝐫𝐲• From mold, EMFs, radiation, viruses, spike proteins, medications, or infections
• Damaged mitochondria = oxygen is present but can’t be used (called pseudohypoxia)
𝐒𝐡𝐚𝐥𝐥𝐨𝐰 𝐁𝐫𝐞𝐚𝐭𝐡𝐢𝐧𝐠 & 𝐒𝐞𝐝𝐞𝐧𝐭𝐚𝐫𝐲 𝐋𝐢𝐟𝐞𝐬𝐭𝐲𝐥𝐞
• Reduces lung oxygen intake, blood flow, and fascia movement
• Also triggers sympathetic dominance (stress mode), further reducing oxygenation
𝐅𝐚𝐬𝐜𝐢𝐚𝐥 𝐨𝐫 𝐋𝐲𝐦𝐩𝐡𝐚𝐭𝐢𝐜 𝐒𝐭𝐚𝐠𝐧𝐚𝐭𝐢𝐨𝐧
• Fascia is a semi-conductive, fluid-rich system — if it’s tight, water-bound, or scarred, oxygen delivery suffers
• Lymph must flow freely to drain waste and deliver oxygenated plasma
𝐋𝐨𝐰 𝐒𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞𝐝 𝐖𝐚𝐭𝐞𝐫 𝐈𝐧𝐬𝐢𝐝𝐞 𝐂𝐞𝐥𝐥𝐬
• EZ water (H₃O₂) holds charge, guides flow, and supports oxygen transfer
• If you’re low on minerals, light, or hydration structure — your cells can’t "breathe"
𝐓𝐢𝐬𝐬𝐮𝐞 𝐀𝐜𝐢𝐝𝐢𝐭𝐲
• Lactic acid buildup from fermentation or poor drainage lowers cellular pH
• Low bicarbonate reserves impair buffering capacity and oxygen binding (Bohr effect)
𝐈𝐧 𝐓𝐡𝐢𝐬 𝐒𝐭𝐚𝐭e inflammation drives all inflammation and injury
• Low oxygen — can’t perform oxidative phosphorylation
• High glucose — fuel for fermentation
• Acidic terrain — fermentation creates lactic acid buildup
• Blocked detox — toxins recirculate, damaging mitochondria
• Weak mitochondria — damaged energy factories = loss of control
• High ROS (reactive oxygen species) — causes DNA damage
• Suppressed immune response — cancer can hide in the chaos
• Poor mitochondrial signaling — apoptosis (cell death) pathways disabled
𝐘𝐎𝐔 𝐂𝐀𝐍 𝐑𝐄‑𝐎𝐗𝐘𝐆𝐄𝐍𝐀𝐓𝐄 𝐓𝐇𝐄 𝐓𝐄𝐑𝐑𝐀𝐈𝐍
Here's a guide to the most powerful tools available, rooted in biology, light, breath, movement, minerals, and energy
𝟏: 𝐎𝐱𝐲𝐠𝐞𝐧 𝐈𝐧𝐩𝐮𝐭𝐬 — 𝐁𝐫𝐞𝐚𝐭𝐡𝐞 𝐈𝐭, 𝐌𝐨𝐯𝐞 𝐈𝐭, 𝐀𝐜𝐭𝐢𝐯𝐚𝐭𝐞 𝐈𝐭
𝟏. 𝐃𝐢𝐚𝐩𝐡𝐫𝐚𝐠𝐦𝐚𝐭𝐢𝐜 𝐁𝐫𝐞𝐚𝐭𝐡𝐢𝐧𝐠
Shallow, stress-based chest breathing keeps oxygen in the upper lungs, where fewer blood vessels exist. Diaphragmatic breathing pulls air into the lower lobes, where 70–80% of gas exchange occurs
Practices:
• 4-7-8 breathing: Inhale 4s, hold 7s, exhale 8s
• The four part breathe also know as Box breathing: Inhale-hold-exhale-hold (all 4s)
• Buteyko method: Focuses on slow, controlled nasal breathing and CO₂ tolerance training. The Bohr effect means higher CO₂ levels allow more oxygen to be released into tissues — paradoxical but critical for deep oxygenation
Breathing through the nose also triggers nitric oxide production in the sinuses — a potent vasodilator and antimicrobial gas that opens airways and blood vessels, enhancing oxygen uptake.
𝟐. 𝐀𝐞𝐫𝐨𝐛𝐢𝐜 𝐌𝐨𝐯𝐞𝐦𝐞𝐧𝐭 & 𝐑𝐞𝐛𝐨𝐮𝐧𝐝𝐢𝐧𝐠
Movement increases heart rate and breathing rate, improving blood oxygen delivery, lymphatic drainage, and tissue oxygenation. It also stimulates mitochondrial biogenesis, especially low-intensity steady-state cardio (Zone 2).
Best practices:
• Rebounding or gentle jumping stimulates lymph
• Brisk walking in nature oxygenates tissues + grounds the body
• Yoga and breath-led movement align fascia and circulation
• Avoid overtraining, which can increase lactate, cortisol, and oxidative stress
𝟑. 𝐂𝐨𝐥𝐝 𝐄𝐱𝐩𝐨𝐬𝐮𝐫𝐞 (𝐇𝐨𝐫𝐦𝐞𝐭𝐢𝐜 𝐒𝐭𝐫𝐞𝐬𝐬)
Cold plunges and showers create a controlled stressor that forces the body to adapt, increasing brown fat activation, oxygen demand, and mitochondrial activity.
Benefits:
• Upregulates uncoupling proteins, improving mitochondrial efficiency
• Increases oxygen delivery during post-cold rewarming
• Enhances vagus nerve tone and nitric oxide synthesis
Tips:
• Start with 30s to 2 minutes
• Use full body (not just face/hands)
• Always warm up afterward (sunlight, red light, movement)
⚠️ Not recommended for individuals with uncontrolled cardiovascular conditions, Raynaud’s disease, or severe adrenal fatigue unless guided by a practitioner.
𝟐: 𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐓𝐨𝐨𝐥𝐬 𝐭𝐨 𝐈𝐦𝐩𝐫𝐨𝐯𝐞 𝐎𝐱𝐲𝐠𝐞𝐧 𝐔𝐬𝐞
𝟒. 𝐑𝐞𝐝 & 𝐍𝐞𝐚𝐫-𝐈𝐧𝐟𝐫𝐚𝐫𝐞𝐝 𝐋𝐢𝐠𝐡𝐭 (𝟔𝟔𝟎–𝟖𝟓𝟎 𝐧𝐦)
Red/NIR light penetrates 3–8 cm into tissue and stimulates cytochrome c oxidase, the 4th complex in the ETC. This directly enhances oxygen binding and ATP output.
Sources:
• Sunlight at sunrise/sunset (low-UV times)
• Red light therapy panels (660/850 nm blend)
• Infrared sauna (heats tissue & boosts oxygen via sweating)
Timing:
• Morning light = circadian regulation + ATP boost
• Evening light = calm parasympathetic tone, healing
𝟓. 𝐌𝐞𝐥𝐚𝐭𝐨𝐧𝐢𝐧 (𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐅𝐨𝐫𝐦)
Melatonin is not just secreted by the pineal gland — each mitochondrion can produce its own melatonin, where it acts as a direct antioxidant and protector of oxygen-using enzymes.
Melatonin:
• Neutralizes reactive oxygen species (ROS)
• Protects Complexes I & IV in the ETC
• Regulates mitophagy and biogenesis
• Rebuilds mitochondrial membranes
Support melatonin by:
• Blocking blue light at night
• Sleeping in total darkness
• Supplementing with liposomal or low-dose oral melatonin in older adults or EMF-exposed individuals (only if needed)
• Consuming melatonin-rich foods: tart cherries, red grapes, cacao, goji berries, walnuts
𝟔. 𝐌𝐞𝐭𝐡𝐲𝐥𝐞𝐧𝐞 𝐁𝐥𝐮𝐞 (𝐀𝐝𝐯𝐚𝐧𝐜𝐞𝐝)
This compound serves as an electron carrier, bypassing damaged ETC complexes and facilitating oxygen use. It:
• Enhances memory and focus
• Protects neurons and mitochondria
• Improves oxygen efficiency in hypoxic states
Use only under supervision, in doses
