The Cole Center for Healing

11/21/2025

More issues with the internet:

A new study of nearly 100,000 people found heavy short-form video use on sites like TikTok and Instagram Reels weakens cognitive function.

Excessive short-form video viewership was linked to poor attention, anxiety, social isolation and sleep issues.

Repeated exposure desensitizes users to slower tasks, reducing cognitive endurance and sustained focus.

Lan Nguyen, et. al. Feeds, Feelings, and Focus:
A Systematic Review and Meta-Analysis Examining the Cognitive and Mental Health Correlates of Short-Form Video Use. Psychological Bulletin, 2025, Vol. 151, No. 9, 1125–1146
ISSN: 0033-2909

The resurgence of short-form videos (SFVs), popularized by TikTok and Douyin, has transformed social media platforms, with features like Instagram Reels and YouTube Shorts fostering their widespread adoption. Although initially geared toward entertainment, SFVs are increasingly used in education, po...

11/21/2025

I have stated for years that persistent infections are the underlying cause of many symptoms and conditions. This is another finding supporting this conclusion.

Epstein-Barr virus (EBV) has been making waves as a candidate driver of diseases like multiple sclerosis and Long Covid. It has also long been linked to systemic lupus erythematosus (SLE), although the “why” behind this link has not been defined. Here, Younis et al. provide evidence for a link between EBV infection and disease development.

Now we have some insight into how EBV affects these conditons. The best therapy for this and other persistent infections is Low Dose Immunotherapy (LDI), which can completely reverse these symptoms. Call us at 513-563-4321 for more info and to schedule an evaluation.

SHADY YOUNIS, et. al. Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus. SCIENCE TRANSLATIONAL MEDICINE, 12 Nov 2025, Vol 17, Issue 824.
DOI: 10.1126/scitranslmed.ady0210

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11/18/2025

I have been discussing the effects of persistent infections on ANY symptoms, including emotional/psychological. Here's ANOTHER study confirming this.

Led by psychiatrist Rosalie Greenberg, the study examined the medical charts of 37 children and adolescents—ages 9 to 17—diagnosed with pediatric bipolar disorder in a Lyme-endemic region of New Jersey.

92% of these patients (34 out of 37) showed evidence of tick-borne disease exposure.

Babesia was detected in 51% (19 out of 37)
Bartonella in 49% (18 out of 37)
Mycoplasma pneumoniae in 38% (14 out of 37)
Borrelia burgdorferi (the Lyme disease bacterium) in 22% (8 out of 37)
Group A Streptococcus in 19% (7 out of 37)
Furthermore, 30 of the 37 children—about 8 out of 10—had both lab test results and symptoms that pointed to infection.

Many of the children had multiple infections, and most showed symptoms consistent with PANS/PANDAS—a set of conditions known to cause abrupt psychiatric changes following infection.

And from the study itself:

Discussion: More than three-quarters of the cohort demonstrated confirmed tick-borne infections. Overlaps between bipolar disorder and tick-borne illness—such as immune dysregulation, chronic symptomatology, and responsiveness to treatments like minocycline and anti-inflammatory agents—support further exploration of infectious contributors to pediatric bipolar disorder. While limited by its single-practice retrospective design, these findings suggest that tick-borne pathogens may play a role in the pathogenesis of bipolar symptoms in youth, warranting larger, controlled studies.

The BEST therapy for these infections is Low Dose Immunotherapy (LDI). No other therapy addresses the immune system dysfunction caused by these infections. If you have any symptoms, especially if no cause has been found, contact us at 513-563-4321 to set up an evaluation.

Greenberg R (2025) Investigating the frequency of tick-borne infections in a case series of 37 youth diagnosed with pediatric bipolar disorder. Front. Child Adolesc. Psychiatry 4:1685016. doi: 10.3389/frcha.2025.1685016

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11/18/2025

As I predicted several years ago, it would take time to see the full effects of Covid vaccines. And now the data is coming out, confirming my worst fears.

This study used a rigorous actuarial approach to estimate ex‑
cess mortality across German federal states during the first
three years of the COVID‑19 pandemic. Regional trends were
analysed alongside associations with state‑level indicators: re‑
ported COVID‑19 deaths and infections, policy stringency, vac‑
cination rates, demographic and socioeconomic factors. Aver‑
age excess mortality was moderate in the first year, with sub‑
stantial regional variation. It increased slightly in the second
year, with stable regional patterns. In the third year, excess
mortality rose sharply, regional differences diminished, and
the most affected states shifted, indicating the emergence of a
new excess mortality driver. In the first two years, excess mor‑
tality strongly correlated with COVID‑19 deaths, although re‑
ported COVID‑19 deaths substantially exceeded excess deaths.
Despite rising excess mortality, COVID‑19 deaths declined
over time. In the third year, only vaccination rate and trust in
institutions showed notable associations, with the latter fully
mediated by vaccination rate. Higher vaccination rates corre‑
lated with larger increases in excess mortality and with smaller
declines in COVID‑19 deaths and case fatality rates, even af‑
ter adjusting for prior mortality levels and time‑invariant con‑
founders. This robust finding underscores the need for urgent
investigation into potential unintended effects of vaccination
or other previously neglected mortality drivers.

The more Covid vaccines given, the higher the death rate in year 3.

Kuhbandner C, Reitzner M. 2025 Regional patterns of excess mortality inGermany during the COVID-19 pandemic: a
state-level analysis. R. Soc. Open Sci. 12: 250790.

11/17/2025

I am often asked why other doctors don't use some of the therapies that I do. This article gives a good explanation, and the full articel is worth a read.

Dr. Mendelsohn, who in his 1979 book, Confessions of a Medical Heretic argued that medicine was a dogmatic institution that prioritized authority, control, and ritualistic practices (which were treated as infallible doctrines requiring blind obedience from patients) over patient well-being, data transparency, and evidence-based care. There, he:

•Highlighted “unwritten rules” in medicine, such as doctors compulsively rushing to prescribe new drugs before their side effects are fully known, as examples of this rigid, faith-like adherence to protocol over science (particularly since debacles routinely followed this blind faith in new pharmaceutical drugs).

•Demonstrated how many routine practices and procedures caused significantly more harm than benefit (e.g., x-rays for tonsillitis later creating thyroid cancer) but could not be challenged due to the dogmatic nature of medicine, leading to similar debacles being repeated in each ensuing decade.

•Demonstrated that many illnesses that are routinely treated with (harmful) interventions would recover on their own, especially if augmented with simple natural healing practices.

•Argued that medicine’s tendency to withhold foundational medical information from the public (hence forcing them to trust the doctor’s opinion rather than their own judgement) was fundamentally unethical.
Note: this critique was raised in the pre-internet age where medical journal information was not widely available to the public. I believe this in part explains why journal articles published at this time (many of which I cite in this newsletter) were much more candid, whereas in later decades information which potentially incriminated the medical profession rarely made it to publication.

•Argued medicine’s compulsion to “do something” as a faith-based impulse rather than rational care, equating medical overreach with religious zeal that harms believers.

•Noted that in addition to patients being attacked for challenging the faith, doctors who did were treated as heretics and cast out (e.g., by being forced to resign from the hospitals they worked at).

10/27/2025

The Cole Center for Healing is a family, practice, specializing and holistic/integrative medicine. If you have been struggling with health issues that you can’t seem to find the answer to or just want to improve your health we can help in our practice we see patients from all over the world for things from newborn baby check ups to stage for cancer

10/26/2025

The body is a unit, and everything effects everything! Here's info on one of those types of effects.

These studies show that periodontal disease was linked to increased white matter damage, raising concerns for brain health. White matter hyperintensities are a silent expression of cerebrovascular disease, and they are "in no way a benign neuroimaging finding," one author emphasized. "A large body of evidence has shown that severe white matter hyperintensities are associated with an increased risk of dementiaopens in a new tab or window, mortality, and various functional deficits."

In addition, poor oral health also raised the risk of ischemic stroke and major cardiovascular events.

So, keep brushing and flossing those teeth! In many cases there are oral infections occurring. The Cole Center has therapies for these problems, with the main treatment being Low Dose Immunotherapy (LDI).

If you're having any of the above issues, call us at 513-563-4321 for more info on how to address these problems.

Meyer J, et al "Periodontal disease independently associated with white matter hyperintensity volume: a measure of cerebral small vessel disease" Neurol Open Access 2025; DOI: 10.1212/WN9.0000000000000037.

Wood S, et al "Combined influence of dental caries and periodontal disease on ischemic stroke risk" Neurol Open Access 2025; DOI: 10.1212/WN9.0000000000000036.

Pantoni L "Taking care of mouth health to prevent cerebrovascular diseases" Neurol Open Access 2025; DOI: 10.1212/WN9.0000000000000042.

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10/25/2025

I have warned about the use of these drugs for years, and now another risk factor has been found, and it's a serious one.

Prescribed use of anxiolytics, hypnotics and sedatives, or antidepressants was associated with a significantly increased risk for future development of amyotrophic lateral sclerosis (ALS) and a worse prognosis after diagnosis compared to nonuse, a large case-control study showed.

ALS has a survival time of 4 years on average, and there is no treatment or cure at this time. There are usually other options to these drugs. If you are taking any of these drugs or want to find out about other approaches, call us at 513-563-4321 for more information.

Charilaos Chourpiliadis, et al. Use of Common Psychiatric Medications and Risk and Prognosis of Amyotrophic Lateral Sclerosis. JAMA Netw Open, Published Online: June 4, 2025
2025;8;(6):e2514437. doi:10.1001/jamanetworkopen.2025.14437

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10/22/2025

Diet is a ciritical factor in health. This study looked at one aspect that sets the tone for the rest of the day.

According to the National Heart, Lung, and Blood InstituteTrusted Source, metabolic syndrome is having at least three of these five conditions: abdominal obesity, high blood sugar, high blood pressure, high triglycerides, and low “good cholesterol.”

People who have metabolic syndrome can then be at an increased riskTrusted Source for several health problems, like heart failure, type 2 diabetes, and organ damage.

A systematic review and meta-analysis published in Nutrients found that not eating breakfast may increase the risk for metabolic syndrome, including high blood pressure and glucose levels.

The study notes that skipping breakfast may impact metabolic health and “the body’s ability to process nutrients” by breaking the body’s natural rhythm.

The Cole Center has developed a diet plan that incorporates this and other research on diet to provide clear directions on healthy eating. Call our office at 513-563-4321 for more info.

Yang, B.; Lian, L.; Xing, K.; Cen, Y.; Zhao, Y.; Zhang, Y. Association of Skipping Breakfast with Metabolic Syndrome and Its Components: A Systematic Review and Meta-Analysis of Observational Studies. Nutrients 2025, 17, 3155.

Objective: Metabolic syndrome (MetS) represents a growing and significant public health burden worldwide. The evidence regarding whether skipping breakfast affects the development of MetS and its components remains inconsistent and uncertain. This study aimed to synthesize the best available evidenc...

10/19/2025

Another study that validates the approach we take with cancer.

Glioblastoma is the most aggressive malignant tumor overall and remains an incurable neoplasm with a median survival of 15 months.

This is a case of glioblastoma multiforme in a patient with a poor prognosis who, following partial removal of the neoplasm, refused conventional therapy consisting of a combination of radiotherapy and temozolomide-based chemotherapy due to personal serious side effects. The patient started an unconventional therapeutic path by alternating periods of oxygen–ozone therapy with concomitant administration of legal medical cannabis products and melatonin. This approach resulted in a complete and durable remission of the disease and long survival.

The ozone was administered rectally rather than by IV, yet gave excellent results. At The Cole Center these agents are part of our Metabolic Therapy approach to cancer. Call us at 513-563-4321 for more info on this and other therapies to improve your health and well being.

Antonini M, et. al. The Effects of a Combination of Medical Cannabis, Melatonin, and Oxygen-Ozone Therapy on Glioblastoma Multiforme: A Case Report. Reports (MDPI). 2023 May 5;6(2):22. doi: 10.3390/reports6020022. PMID: 40729189; PMCID: PMC12225241.

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10/19/2025

Well, this isn't good:

The study: To evaluate the association between statin therapy, cardiorespiratory fitness (CRF), body mass index (BMI), and type 2 diabetes mellitus (T2DM).

High-intensity statin therapy was associated with an increased risk of T2DM. The risk increased progressively with higher BMI and decreased with higher CRF.

In other words, the long term use of statins increased the rates of Type 2 Diabetes. The good news is that The Cole Center has other options to address these issues that actually increase your state of health. Contact us at 513-563-4321 for more info.

Diabetes Incidence According to Statin Intensity Regimen, Body Mass Index, and Cardiorespiratory Fitness. Kokkinos, Peter et al.
Mayo Clinic Proceedings, Volume 0, Issue 0

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10/18/2025

Once again, junk food is a problem:

Soft drink consumption is linked to a higher risk for major depressive disorder (MDD) and more severe symptoms in women, potentially due to alterations in the gut microbiome, new research showed.

“Our findings add to the growing evidence that high intake of sugar-sweetened and artificially sweetened beverages is linked to depression risk and severity, potentially through gut-brain mechanisms,” stated lead investigator Sharmili Edwin Thanarajah, MD.

The results were published online on September 24, 2025, in JAMA Psychiatry.

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