Purdue Institute for Cancer Research

Purdue Institute for Cancer Research The Purdue University Center for Cancer Research is the oldest NCI funded Cancer Center in the state of Indiana.

The Purdue Institute for Cancer Research is a National Cancer Institute-designated basic research cancer center leading the way in early detection, prevention, diagnostics, and life-changing therapies.

For both Nathaniel Mabe and Andrew Kinder, the fight against cancer is personal — and it's one inspired by the life and ...
03/12/2026

For both Nathaniel Mabe and Andrew Kinder, the fight against cancer is personal — and it's one inspired by the life and legacy of Tyler Trent.

Mabe is a member of the Purdue Institute for Cancer Research and assistant professor of medicinal chemistry and molecular pharmacology working to develop new therapies to combat pediatric cancer, with a focus on neuroblastoma, a malignant cancer that originates in a child’s nerve tissue.

Kinder is a Purdue senior set to graduate this year from the Purdue University Daniels School of Business who spent his freshman year undergoing chemotherapy for leukemia.

Neither let their diagnosis define them. Both let it drive them.
https://purdue.link/Mabe-Kinder.cancer

Purdue College of Pharmacy

Cancer is really a problem of cells "forgetting" what they're supposed to be.Purdue researcher Emily Dykhuizen studies t...
03/12/2026

Cancer is really a problem of cells "forgetting" what they're supposed to be.

Purdue researcher Emily Dykhuizen studies the molecular machinery that controls which genes a cell can access, and what happens when cancer exploits that system to evade the immune system, resist treatment and spread.

She designs molecules that selectively inhibit the chromatin regulators driving those processes. Her lab is currently testing inhibitors designed to control metastasis in breast cancer.

📰 Check out the full story, "Exploring the machinery that surrounds DNA to stop cancer," here: https://purdue.link/ED-cancer-machinery

How do Purdue cancer discoveries move from the laboratory to helping patients?That question anchored two events this wee...
03/07/2026

How do Purdue cancer discoveries move from the laboratory to helping patients?

That question anchored two events this week in Austin, Texas, where PICR Director Andrew Mesecar joined community members, alumni and technology leaders for conversations about Purdue's impact in cancer research and the future of the field.

At a talk hosted by the The Austin Forum on Technology & Society and a “Dinner with the Director” organized in partnership with the Purdue Alumni Club of Austin, Mesecar shared how advances in AI, liquid biopsy technologies and personalized medicine are reshaping the field.

He also highlighted FDA-approved innovations developed by Purdue researchers, demonstrating how discoveries made through basic science research translate into new diagnostic tools and therapies.

Thank you to everyone in the Austin community who joined the discussion, asked thoughtful questions and shared their own experiences with cancer.

Catch the full recap: purdue.link/purdue-cancer-talks-atx

We are profoundly saddened to share the passing of Philip Low, one of the most influential scientists in the history of ...
03/05/2026

We are profoundly saddened to share the passing of Philip Low, one of the most influential scientists in the history of Purdue cancer research.

Low devoted his career to transforming fundamental discoveries into therapies that save lives, with pioneering work leading to multiple FDA-approved cancer drugs and agents. Over the course of his career, he held more than 100 U.S. patents and founded seven companies to bring Purdue discoveries from the laboratory to patients around the world.

Through his research, mentorship and entrepreneurial leadership, Low helped define Purdue’s global impact in drug discovery and precision cancer therapeutics. His legacy will continue to shape cancer research and improve lives for generations to come. https://purdue.link/a87ijm

Every cancer story has a beginning.We are determined to deliver a better ending.To close the gap between diagnosis and d...
02/27/2026

Every cancer story has a beginning.
We are determined to deliver a better ending.

To close the gap between diagnosis and defeat.

At the Purdue Institute for Cancer Research, scientists from disciplines across campus — from Purdue Science to Purdue University College of Veterinary Medicine & Veterinary Hospital — study cancer at its origin, uncovering how it forms, how it survives and how it can be stopped.

For nearly 50 years, this sustained pursuit of discovery has earned national recognition for scientific rigor and impact, placing Purdue among a small group of NCI-designated Basic Laboratory Cancer Centers.

A Purdue discovery is advancing in the clinic.Gibson Oncology and the National Institutes of Health have initiated a Pha...
02/25/2026

A Purdue discovery is advancing in the clinic.

Gibson Oncology and the National Institutes of Health have initiated a Phase 2 clinical trial of LMP744 for patients with first-time recurrent glioblastoma — an aggressive brain cancer with limited treatment options after recurrence.

LMP744 was designed and synthesized at Purdue by a research group led by Mark Cushman, a member emeritus of the Purdue Institute for Cancer Research and former faculty in Purdue College of Pharmacy. The compound advances a dual mechanism targeting topoisomerase 1 and cMYC overexpression.

The Phase 2 study will evaluate tumor regression in approximately 40 patients, with secondary endpoints including progression-free survival, biological response and overall survival.

This milestone reflects the trajectory of basic discovery at Purdue University translating into human trials, supported by strategic patenting and licensing through the Purdue Innovates Office of Technology Commercialization. https://purdue.link/glioblastoma-trial

Purdue welcomed National Institutes of Health (NIH) Director Dr. Jay Bhattacharya to campus last week. During the visit,...
02/23/2026

Purdue welcomed National Institutes of Health (NIH) Director Dr. Jay Bhattacharya to campus last week. During the visit, Bhattacharya met with campus research leaders, including Purdue Institute for Cancer Research Director Andrew Mesecar and PI4D Director Richard Kuhn.

The conversation highlighted Purdue’s capabilities in biomedical research and its alignment with the NIH mission to enhance health, lengthen life and reduce illness and disability. Dr. Mesecar emphasized Purdue's strengths in cancer research, including development of targeted cancer therapeutics, structural biology, drug design, medicinal chemistry, and clinical trials in canines.

We value continued dialogue with national research leaders about advancing rigorous, curiosity-driven science, and appreciate the opportunity to share how NIH-supported research at Purdue contributes to scientific progress, innovation and workforce development that benefit Indiana and beyond.

Boilermaker fans and the PICR crew are in Mackey tonight for the Purdue Women's Basketball game — and Hammer Down Cancer...
02/20/2026

Boilermaker fans and the PICR crew are in Mackey tonight for the Purdue Women's Basketball game — and Hammer Down Cancer night means this game is dedicated to raising support for cancer research at Purdue University.

During the game, PICR member Kyle Cottrell and Purdue Biochemistry graduate student Addison Young were recognized on court for their team's contributions to cancer research, including the discovery of a new therapeutic target for triple-negative breast cancer.

The game-worn jersey auction is live through tonight! Bid or make a donation: https://one.bidpal.net/wbbhdc26

Purdue Agriculture

02/17/2026

Make your bids for game-worn Hammer Down Cancer jerseys 🩷

bidpal.net/wbbhdc26

This work belongs to all of us, and we do it all for love.Happy Valentine's Day 💛🖤
02/14/2026

This work belongs to all of us, and we do it all for love.
Happy Valentine's Day 💛🖤

Today is about honoring the women at Purdue University and around the world who are transforming science.👉 But it is als...
02/11/2026

Today is about honoring the women at Purdue University and around the world who are transforming science.

👉 But it is also about protecting the path behind them.

Tomorrow, and every day after, we commit to building an environment where the next generation of women will have every opportunity to push the frontiers of cancer research. To lead labs, launch startups, bring lifesaving ideas to life.

Join us in celebrating International Day of Women and Girls in Science.

| Purdue Science | Purdue College of Pharmacy

🌴 Kicking off Purdue for Life Foundation's Naples ’26 with a happy hour!PICR Director Andrew Mesecar discusses how Pur...
02/10/2026

🌴 Kicking off Purdue for Life Foundation's Naples ’26 with a happy hour!

PICR Director Andrew Mesecar discusses how Purdue research is shaping what’s next in cancer discovery. We're looking ahead to a One Health Back-to-Class session later this week — researchers Deborah Knapp and Nadia Lanman will share how the Purdue Institute for Cancer Research leverages AI and machine learning to power breakthroughs in cancer research.

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201 S University Street, Hansen Building Room 141
West Lafayette, IN
47907

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Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

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