17/11/2025
Would you use psychedelics to support your own mental health? 🤔🌌🧠
Check my bio for link to the full study 👈
🔑 Key Takeaways of the Study
-5-MeO-DMT acts extremely fast, with effects starting in 0–2 minutes, peaking by 8–15 minutes, and fading within an hour.
-The experience is dominated by strong bodily sensations like floating, tingling, warmth, and loss of body awareness.
-Emotions become extremely intense, often shifting rapidly between fear, sadness, joy, and relief.
-Visual effects are minimal and simple, unlike the complex imagery seen with other psychedelics.
-Participants often experience major changes in their sense of self, including feelings of expansion, dissolution, or entering a void-like space.
-The single biggest factor shaping whether the experience feels difficult or meaningful is the person’s ability to surrender rather than resist.
-The 5-MeO-DMT journey follows a consistent timeline: somatic onset, emotional peak, cognitive recovery, and afterglow.
-This study is the first to map the 5-MeO-DMT experience in moment-by-moment detail using microphenomenology combined with AI-based topic modeling.
Reference: Ermakova et al. Mapping the phenomenology of intranasal 5-MeO-DMT in psychedelic-naïve healthy adults. Sci Rep 15, 38874 (2025).