01/17/2026
Have you been struggling with your blood sugar regulation? If so, you are not alone, and it's a really good idea to check your insulin (in addition to your glucose and A1c). If you can’t access insulin-specific tests like the HOMA-IR index, you need look no further than the ALT and AST readings on your standard liver enzyme panel.
New research shows that a higher ALT-to-AST ratio is a strong indicator of insulin resistance, especially in women. It’s such an easy test. You don’t even need to fast.
Other clues to insulin resistance include high triglycerides (>150 mg/dL or 1.7 mmol/L), low HDL, constant hunger, reactive hypoglycemia, and weight gain around the middle.
Insulin resistance is the most common hormonal condition and a driver of many downstream problems. So it’s worth knowing if you have it, not guessing.
The BEST NEWS: Insulin resistance CAN be reversed. Ask me how!
Insulin resistance is a common pathophysiology in patients with type 2 diabetes mellitus, cardiovascular disease, and non-alcoholic fatty liver disease. Thus, screening for the risk of insulin resistance is important to prevent disease progression. We evaluated the alanine aminotransferase/aspartate...