05/02/2021
C19 Friday night update:
The numbers have continued to decline, but Covid is not gone.
Guess we will see the virus around till we have herd immunity. That means continued infection or vaccination is the only way to stop the pandemic.
With not much happening, I thought I'd give an update on the expected vaccines South Africa will get and how they work.
The one that has already landed in ZA is the Astra Zeneca Oxford (AZO) vaccine. AZO is a vector vaccine.
Currently, there are two types of Coronavirus vaccines - vector and generic (mRNA) vaccines.
Vector:
Astra Zeneca Oxford (UK)
Johnson and Johnson (US)
Sputnik (Russia)
Sinopharm (China)
mRNA:
Pfizer
Moderna
The aim of all these vaccines is to produce a piece of the outside of the virus (antigen) for the body to produce antibodies (IgM and IgG). Antibodies are the body’s natural defence and will then recognise future attacks of the virus with an immune response.
The short way to explain the antigen production is that the mRNA vaccine skips one step in getting the body to produce the antigen. An injection of a tiny piece of mRNA (generic material) for the body to absorb and make a spike protein of the virus - brilliant.
The vector viruses use another deactivated virus, in this case, an Adenovirus, to deliver the piece of genetic material via infection to trick the body to make the spike protein.
The challenge for us in ZA (and everywhere else) is to keep a cold chain at minus 20Celcius (Moderna) or minus 70Celcius (Pfizer). No one is set up to keep that amount of vaccines at dry ice type temperatures.
We should be OK with the cold chain of Astra Zeneca and J&J, as that we do daily with fridge (2-4Celcius) temperatures.
All in all, the results coming through is looking better and better.
I for one cannot wait to get my shot - hopefully in the next week or two.
Stay healthy people and wear your masks.
**Get better our sister currently in the ward fighting the C19 (you know who you are) - we are praying for your protection.**