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Monday 08:00 - 15:30 Tuesday 08:00 - 15:30 Wednesday 08:00 - 17:00 Thursday 08:00 - 17:00 Friday 08:00 - 17:00

TREAD Research

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TREAD Research

TREAD is a large, award-winning clinical trial unit. Pioneering Clinical Trials. Empowering Health. Changing Lives. Professor Anton F.

The unit is run by Professor Lesley Burgess who has been involved in clinical trials since 1992. In addition to being a qualified medical doctor, she also has a MMed and PHD from Wits University, a post-graduate diploma in International Research Ethics from University of Cape Town and a MSc (Clinical Research) from Liverpool University. She spent a number of years sitting on the Stellenbosch University Health Research Ethics Committee and is currently a reviewer of the Clinical Trials Committee of the Medicines Control Council. Additional research experience includes Steering Committee membership, DSMB membership and she is actively involved in GCP and clinical trial training and site capacity building. Doubell is a Co- founder of TREAD and Head of Cardiology, Tygerberg Hospital and University of Stellenbosch. He completed his medical degree at the University of Stellenbosch in 1979, graduating as the top student of that year. He is the chairman of the Tygerberg branch of the South African Heart Association and a past-president of the South African Heart Association (two consecutive terms from 2000 to 2004). He currently still serves on the Exco of the South African Heart Association and is the Editor of SAHeart, the official Journal of the South African Heart Association.

20/02/2026

❤️ Join heart failure research
Put a whole team behind you 🤝

Our clinical trial is looking for a better way to treat people with heart failure.
Join us today.

The EASi-HF Preserved Trial is looking at an investigational treatment option for people with chronic heart failure (HF).
This investigational treatment option is a combination of an investigational medication with an approved medication for HF.

We are looking for volunteers:
• 18 years of age or older
• Diagnosed with chronic HF at least 3 months ago
• With left ventricular ejection fraction (LVEF) of 40% or higher

To learn whether you might be able to participate, please visit our website:
🌐 www.EASi-HFtrial.com

Or contact us to learn more:
📱 WhatsApp our recruiter to find out if you qualify: 066 472 5713
🌐 www.treadresearch.co.za

This research study was approved by the South African Health Products Regulatory Authority (SAHPRA) and the responsible Ethics Committee.

14/02/2026

This Valentine’s Day, love goes beyond flowers and chocolates.
It’s also about caring for the heart that carries you through life. ❤️

Heart disease often develops quietly, without obvious warning signs.
Taking a moment to check your heart health could protect many more tomorrows with the people you love.

Show your heart some love this February. ❤️
Ask us about our heart health research and clinical trials.

📞 WhatsApp: 066 472 5713
🌐 www.treadresearch.co.za

11/02/2026

Why People Over 40 Should Monitor Heart Health More Closely
As we get older, the body changes in ways we don’t always feel right away.

From around age 40, the risk of certain health conditions begins to rise — including:
• High blood pressure
• Elevated blood sugar or diabetes
• Kidney strain
• Reduced heart function over time

These changes can develop quietly, without obvious symptoms, which is why regular check-ups become more important with age.
Knowing your numbers early can help prevent serious heart problems later.

A simple check today can protect your health for years to come.

Ask us about our heart health research and clinical trials.

📞 066 472 5713 (WhatsApp)
🌐 www.treadresearch.co.za

05/02/2026

🧡Heart Problems After Serious Infections — What You Should Know🧡

In many communities, heart failure is sometimes seen after serious infections that place strain on the body and heart.

These may include:
• TB
• HIV-related complications
• Viral infections
• COVID-19 complications

Heart changes can develop quietly, with symptoms only appearing months or years later.

Early awareness and regular check-ups can make a real difference.
If you’ve had a serious infection and notice fatigue, breathlessness, or low stamina, it’s important to get your heart checked.

Ask us about heart health research and clinical trials.
📞 066 472 5713 (WhatsApp)
🌐 www.treadresearch.co.za

03/02/2026

Many people don’t realise that high blood pressure can run in families and often shows no obvious symptoms. You can feel “fine” while your blood pressure is quietly placing strain on your heart, brain, and kidneys.

That’s why knowing your family history matters.
If parents, grandparents, or close relatives have had:

🩺High blood pressure
🩺Heart disease
🩺Stroke
🩺Diabetes
.. your own risk may be higher, even at a younger age.

The good news?
Early checks, awareness, and support can make a real difference.
Don’t wait for symptoms.

Know your numbers. Protect your heart.

💙Ask us about heart health research and clinical trials.
📞 066 472 5713 (WhatsApp)
🌐 www.treadresearch.co.za

29/01/2026

Heart Symptoms in Women Look Different 🧡
Many people think heart problems always mean sudden chest pain.
But for women, symptoms can look very different.

You might experience:
• Extreme fatigue
• Dizziness or light-headedness
• Nausea
• Back, shoulder, or jaw discomfort
• Shortness of breath during light activity

These signs are easy to dismiss as stress or “just being tired”.
But they matter and your heart could be asking for help.
Listen to your body. Don’t ignore the signs.

Ask us about our heart health clinical trials and support programs.

📞 066 472 5713 (WhatsApp)
🌐 www.treadresearch.co.za

27/01/2026

Do you wake up at night feeling short of breath?

It might feel like:
• Waking up suddenly gasping for air
• Needing to sit up or stand to breathe better
• Sleeping upright to feel comfortable
• Using extra pillows at night

Many people brush this off, but night-time breathing problems can be an early sign that the heart is under strain.

These symptoms often develop slowly and are easy to ignore.
But your body could be asking for help.

If this sounds familiar, don’t ignore it.

Ask us about our heart health clinical trials and support programs.

📞 066 472 5713 (WhatsApp)
🌐 www.treadresearch.co.za

Listen to your heart. Act early.

22/01/2026

Short Breath + Tired Legs?
These are signs you shouldn’t ignore.
When the heart struggles to pump efficiently, the body feels the impact:

• Less blood reaches your muscles
• Breathing becomes harder
• Walking becomes tiring
• Climbing stairs feels exhausting

These symptoms often develop slowly over months or even years and are easy to dismiss as “just getting older” or “being unfit.”
But if everyday activities are becoming harder, your heart may be asking for help.

Early detection can change outcomes.
Listen to your body. Don’t ignore the signs.

👉 Find out what clinical trials are currently running with TREAD and whether you or a loved one may qualify.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

31/12/2025

✨ Welcome to a New Year ✨We wish our patients, staff, research participants, and partners a healthy year ahead. We remain committed to research that supports better health and brighter futures and placing people at the centre of research.

27/12/2025

Repeat Hospital Visits? Here’s Why It Happens.
If you or someone you know has been hospitalised more than once for chest issues, breathlessness, infections, or fluid build-up, there may be underlying reasons:

• Blood pressure not fully controlled
• Heart pumping function weakening over time
• Fluid retention between visits
• Untreated inflammation
• Poor recovery after infection or hospitalisation

Many people don’t realise these symptoms progress slowly.
Early awareness can break the cycle of hospital admissions.

👉 Find out what clinical trials are currently running with TREAD and whether you or a loved one may qualify.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

25/12/2025

🎄 Merry Christmas from Team TREAD 🎄
As the year comes to a close, we’d like to thank our community, partners, and participants for being part of the TREAD Research journey.
May this festive season bring you rest, reflection, and meaningful moments with those you care about most. We look forward to continuing our work together in the year ahead.

22/12/2025

After being sick, your body needs time to recover.
But if weeks or even months have passed and breathing still feels difficult, your body may not be fully healed yet.

You might notice:
• Getting out of breath more easily
• Feeling tired most of the time
• Tightness or wheezing in your chest
• Struggling to walk as far as you used to

Your heart, lungs and immune system work together. When one is still recovering, the others have to work harder too.

👉 If symptoms keep lingering, don’t brush them off.
Your body may be asking for a little extra care.

Find out more about ongoing research and support at TREAD Research.

📱 066 472 5713
📧 info@treadresearch.co.za
🌐 www.treadresearch.co.za

Address

Room 41, 8th Floor Green Avenue Tygerberg Hospital Francie Van Zijl Drive, Parow
Cape Town
7505

Opening Hours

Monday	08:00 - 15:30
Tuesday	08:00 - 15:30
Wednesday	08:00 - 17:00
Thursday	08:00 - 17:00
Friday	08:00 - 17:00

Website

http://tread.co.za/

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