13/02/2026
HOW HIJAMAH STIMULATES THE IMMUNE RESPONSE
From a physiological perspective, Hijamah (wet cupping) stimulates the immune system through a series of local tissue, vascular, and neuro-immune responses.
When suction is applied to the skin, it creates negative pressure that stretches the skin and underlying microvasculature. This mechanical stress causes vasodilation and increases capillary permeability, allowing plasma and immune cells to move more easily into the area.
When superficial incisions are made, a small, controlled injury occurs. The body immediately activates the innate immune response, which is the first line of defense against tissue damage.
This controlled injury triggers:-
Inflammatory signaling
Damaged cells release signaling molecules such as cytokines and chemokines. These act as chemical messengers that recruit white blood cells (neutrophils and macrophages) to the site.
Increased blood flow (hyperemia).
Local vasodilation
improves circulation, delivering oxygen, nutrients, antibodies, and immune cells to the area.
Activation of macrophages
These immune cells remove debris and pathogens and release growth factors that promote tissue repair.
Stimulation of the lymphatic system
The pressure changes may enhance lymphatic drainage, supporting the transport of immune cells and removal of inflammatory byproducts.
Neuro-immune modulation Mechanical stimulation of skin receptors can influence the autonomic nervous system, potentially reducing stress hormones like cortisol. Lower cortisol levels are associated with improved immune responsiveness.
Additionally, the mild blood loss may stimulate the bone marrow to increase production of new blood cells, including certain immune cells, though this effect is generally modest.
Overall, physiologically, hijamah works not by “boosting” immunity in a direct pharmacological way, but by inducing a controlled local inflammatory response, improving microcirculation, and engaging both innate immune mechanisms
