Zambart

Zambart ZAMBART is a Zambian not -for- profit public health research organization. Located at the University

ZAMBART Project has recently completed the largest ever TB/HIV intervention trial – Zambia-South Africa TB and AIDS Reduction (ZAMSTAR), a joint collaboration with the LSHTM and the Desmond Tutu TB Center at Stellenbosch University in South Africa, conducted as part of the CREATE consortium. This trial found that a household level intervention of combined TB/HIV care reduced both the prevalence of tuberculosis in adults and new Tuberculosis infections in children when measured at the community level. ZAMBART is currently conducting the HPTN 071 study / Population effect of Antiretroviral Therapy to reduce HIV, another large cluster randomized trial. In this trial, 21 communities with over 1 million people will be randomly allocated to receive a combination HIV prevention package that includes universal HIV testing with the offer of immediate access to ART to those found HIV positive regardless of their CD4 count, medical male circumcision, and provision of VCT and condoms at household level.

26/11/2025
Minister of Technology and Science Visits Zambart Stand at the 2025 Zambia Science Conference.Zambart today proudly part...
26/11/2025

Minister of Technology and Science Visits Zambart Stand at the 2025 Zambia Science Conference.

Zambart today proudly participated in the opening day of the Annual Zambia Science Conference, held as part of the 2025 National Science Week at the Mulungushi International Conference Centre (MICC). The national event, organised by the National Science and Technology Council (NSTC) in partnership with the University of Zambia (UNZA) and other key stakeholders, is being held under the theme: “Harnessing STI for a Resilient Zambia: Innovative Solutions for Sustainable Growth and Inclusive Development.”

Zambart’s exhibition stand received a special highlight during the conference when the Minister of Technology and Science, Honourable Felix C. Mutati, MP, visited the stand. The Minister engaged with the Zambart team, acknowledging the institution’s longstanding role in advancing infectious disease research, operational studies, and community-centred innovation.

The Zambart team presented ongoing work in HIV, TB, STI and emerging public health research areas, including new studies aligned with national priorities on digital innovation and community-engaged science.

By participating in this year’s conference, Zambart reaffirms its mission to advance locally relevant scientific solutions that address Zambia’s most pressing public health challenges. The institution continues to work closely with government, communities, academic institutions, and global partners to improve health outcomes and contribute to the national development agenda.



Integration of HIV pre-exposure prophylaxis and dual HIV/syphilis testing into antenatal and postnatal care in Lusaka, Z...
25/11/2025

Integration of HIV pre-exposure prophylaxis and dual HIV/syphilis testing into antenatal and postnatal care in Lusaka, Zambia

Vertical (mother-to-child) transmission of HIV and syphilis continues to contribute to adverse maternal and perinatal outcomes in Zambia. The country faces a high HIV burden, with an estimated prevalence of 8.7% among adults aged 15–49 years in 2023. Adolescent girls and young women (15–24 years) accounted for nearly two-thirds of new infections, and the vertical HIV transmission rate—including breastfeeding—was 6.6% in 2023. The 2015–2018 Population-based HIV Impact Assessment reported a 3% active syphilis prevalence in those aged ≥15 years

Although Zambia has integrated PrEP services and dual HIV/syphilis testing into routine ANC and PNC, limited evidence exists on how these services function in real-world healthcare settings. To address this gap, Instituut voor Tropische Geneeskunde | Institute of Tropical Medicine and Zambart conducted a formative qualitative study in two healthcare facilities in Lusaka to explore how PrEP and dual HIV/syphilis testing are being integrated into ANC/PNC. Participants included Ministry of Health Zambia representatives, ANC/PNC healthcare providers, and pregnant and postpartum women aged 18 years and older.

The study team recently held a local stakeholder meeting to share the findings from this formative research. Results showed that participants valued the integration of PrEP and dual HIV/syphilis testing into ANC/PNC, noting improvements in service efficiency, accessibility, privacy, and clients’ health status awareness. Strengthening integration will require continued investment in robust health systems, supportive policies, and engagement with communities and male partners.

Zambart and ITM look forward to embark on the second phase of the project, funded by the Research foundation Flanders (FWO).

HIV/syphilis testing

GLOBE-HPV Study Shares Preliminary Findings with Local Stakeholders in ZambiaZambia has one of the highest cervical canc...
22/11/2025

GLOBE-HPV Study Shares Preliminary Findings with Local Stakeholders in Zambia

Zambia has one of the highest cervical cancer incidence rates in the world. Cervical cancer remains a major public health concern in the country. High-risk Human Papillomavirus (HR-HPV) 16/18 are responsible for approximately 70% of cervical cancer cases.

Zambart is implementing the Global Burden Estimation of Human Papillomavirus (GLOBE-HPV) Study as part of a multi-country study involving 5 countries in South Sahara Africa and 3 in South Asia. In Zambia, the study aims to estimate the prevalence of HPV 16 and/or 18 infection among girls and women aged 9–50 years in both rural and urban settings, and the incidence of persistent HPV 16 and/or 18 infection among women living with HIV aged 15 to 35 years over a two-year period. The GLOBE-HPV Study is a five-year project (2023–2027) being conducted in Chongwe and Lusaka Districts. Its goal is to inform national strategies for cervical cancer prevention and control by improving understanding of the HPV burden in Zambia.

Recently, the GLOBE-HPV study team hosted a local stakeholder dissemination meeting to share preliminary findings. The early results revealed several important insights including: Low knowledge and uptake of the HPV vaccine persist, particularly in urban sites, women living with HIV are twice as likely to have high-risk HPV 16/18 compared to those not living with HIV, older women (above 20 years) are more likely to have high-risk HPV 16/18 infections than younger women (below 20 years) and finally community engagement has proven essential in bridging research efforts with real-life public health needs.

Stakeholders provided valuable feedback, including the need to expand and focus cervical cancer screening efforts for all women and to consider transitioning from the quadrivalent (4-valent) to the nonavalent (9-valent) HPV vaccine to broaden protection against additional HPV strains.

Gates Foundation Ministry of Health ZambiaLondon School of Hygiene & Tropical Medicine International Vaccine Institute Karolinska Institutet

Happy International Men's Day!"On behalf of Zambart, we wish all the incredible men out there a Happy International Men'...
19/11/2025

Happy International Men's Day!

"On behalf of Zambart, we wish all the incredible men out there a Happy International Men's Day! We celebrate your strength, resilience, and the positive impact you make in our communities.

Thank you for all that you do! 💪👨

Zambart Hands Over State-of-the-Art Bronchoscopy Equipment to Ndola Teaching Hospital Access to Health Zambia, in partne...
17/11/2025

Zambart Hands Over State-of-the-Art Bronchoscopy Equipment to Ndola Teaching Hospital

Access to Health Zambia, in partnership with Zambart, and the Ministry of Health, has taken a major step toward improving early lung cancer diagnosis in Zambia through the Multinational Lung Cancer Control Program (MLCCP). On 14th November 2025, Access to Health Zambia and Zambart officially handed over a state-of-the-art bronchoscopy machine to Ndola Teaching Hospital, marking an important milestone in decentralising lung cancer diagnostic services beyond Lusaka.

The handover is part of MLCCP’s broader goal of strengthening community and health system responses to lung cancer—particularly in Ndola and Kabwe—while generating evidence on the true burden of the disease through research.

Globally, lung cancer remains the leading cause of cancer-related deaths. In Zambia, it ranks among the top ten causes of cancer mortality, although current data largely comes from international estimates due to limited local surveillance. Lung cancer symptoms, such as persistent cough, weight loss, and breathing difficulties, closely overlap with those of tuberculosis (TB), a disease Zambart has worked extensively on for over two decades. While TB testing tools are widely available across primary health facilities, lung cancer often goes undetected because diagnostic tools like bronchoscopy are scarce and centralised.

As Dr Kwame Shanaube, Executive Director of Zambart, noted during the handover ceremony, “Lung cancer often goes undetected or is diagnosed late, partly because diagnostic tools have not been readily available. This equipment will bring great relief to patients who no longer need to travel to Lusaka to access bronchoscopy services.”

The Multinational Lung Cancer Control Program—implemented in Zambia, Kenya, Malawi, Tanzania, South Africa, Ethiopia, and Zimbabwe with support from the Bristol Myers Squibb Foundation—aims to improve early detection, diagnosis, and management of lung cancer through a multi-level approach. In Zambia, the programme focuses on strengthening surveillance systems, expanding diagnostic capacity, and building the skills of health workers. Efforts include enhancing the Zambia National Cancer Registry’s ability to collect and analyse lung cancer data, conducting research studies at the Cancer Diseases Hospital, and improving diagnostic capacity by providing bronchoscopy equipment to both Ndola Teaching Hospital and Kabwe Central Hospital.

The programme is also establishing a Multidisciplinary Team linking the Cancer Diseases Hospital with the two peripheral hospitals to improve case discussions, referrals, and coordinated care. Alongside these clinical efforts, MLCCP is raising awareness of lung cancer risk factors and symptoms in communities such as Mapalo in Ndola and Makululu in Kabwe, while training healthcare providers to recognise, refer, and manage suspected cases more effectively.

The bronchoscopy will significantly enhance the hospital’s ability to diagnose and manage lung cancer. Clinicians will now be able to obtain tissue samples for biopsy, investigate suspected lung cancer cases, diagnose other respiratory conditions, and manage patients presenting with issues such as unexplained cough or foreign body aspiration.

Ministry of Health Zambia to Health Zambia -MYERS SQUIBB PATIENT ASSISTANCE FOUNDATION INC

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