Leaders in Allergy, Asthma and Immune Disease Clinical Research
10/24/2025
A Phase 2, randomized, double-blind, placebo-controlled study to investigate the safety and efficacy in reducing nasal allergen challenge provoked symptoms of treatment with DM-101PX in adults with birch pollen allergic rhinitis or rhinoconjunctivitis.
The overall purpose of the study is to evaluate the safety and tolerability of treatment with DM-101PX and its efficacy in reducing symptoms provoked by Nasal Allergen Challenge (NAC) with birch pollen extract in individuals with moderate to severe birch pollen-induced allergic rhinitis or rhinoconjunctivitis.
Please click on the link below if you are interested in the study:
birch allergy, allergies
09/11/2025
Pre-Screening Study for Participants With Environmental Allergies (including birch) for Future Participation in Research Studies.
The objective of this pre-screening protocol is to pre-screen and confirm eligibility of participants with a documented history of moderate to severe environmental allergic rhinitis/rhinoconjunctivitis due to birch pollen exposure, for participation in clinical studies involving birch allergen-specific immunotherapy at Red Maple Trials.
birch allergy, allergies
09/08/2025
A Pre-Screening Study to Conduct a Future Clinical Study in Participants Allergic to Common Ragweed (Ambrosia artemisiifolia).
This pre-screening study will identify and characterize a patient population with a history of ragweed-induced rhinoconjunctivitis who may benefit from treatment and potentially be included in future interventional studies.
Please click on the link below if you are interested in the study:
A Pre-Screening Study to Conduct a Future Clinical Study in Participants Allergic to Common Ragweed (Ambrosia artemisiifolia)If you are interested in participating in this clinical trial, please fill out the contact form below to speak to one of our Research Coordinators to find out if this study is...
01/31/2025
A Pre-Screening Study to Conduct a Future Clinical Study in Participants Allergic to Common Ragweed (Ambrosia artemisiifolia).
This pre-screening study will identify and characterize a patient population with a history of ragweed-induced rhinoconjunctivitis who may benefit from treatment and potentially be included in future interventional studies.
Please click on the link below if you are interested in the study:
Learn about the VALIANT asthma study. This study is now enrolling adult
participants 18 to 75 years of age with severe asthma. Click to see study details
VALIANT Asthma studyIf you are interested in participating in this clinical trial, please fill out the contact form to speak to one of our Research Coordinators to find out if this study is right for you. The VALIANT studyThe VALIANT study is evaluating a study drug given every 12 weeks to adult par...
11/14/2023
A dermatologic study is enrolling participants in Ottawa to discover new treatment to
improve chronic hives.
What’s next in the fight against COVID-19? The NextCOVE Study is researching an investigational vaccine that may help protect against multiple variants of COVID-19 for individuals ages 12 to 17 who have received a COVID-19 vaccine and individuals ages 18 and older who have received a COVID-19 vaccine and at least 1 booster dose of a COVID-19 vaccine.
See if you or your child may qualify for this important trial.
Learn more at
The purpose of the NextCOVE Study is to evaluate an investigational bivalent vaccine that may protect people from getting sick if they come into contact with the virus that causes COVID-19 and multiple variants, including the Omicron variant.
12/23/2022
Wishing you a safe and happy holiday season.
12/07/2022
COVID-19 Vaccine Survey StudyIf you are interested in participating in this clinical trial, please fill out and submit the quick questionnaire below. Researchers are looking for volunteers to complete the VIP Survey each night - for up to one week following their COVID-19 vaccination appointment ...
12/07/2022
COVID-19 Vaccine Clinical TrialIf you are interested in participating in this clinical trial, please book a time to speak to one of our Research Coordinators to find out if this study is right for you. COVID-19 Vaccine StudyRed Maple Trials is looking for applicants who may be eligible to participat...
11/30/2022
Flu Vaccine Clinical TrialIf you are interested in participating in this clinical trial, please book a time to speak to one of our Research Coordinators to find out if this study is right for you. About the Glow TrialClinical trials, and the volunteers who participate in them, are vital to creating....
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Red Maple Trials is specialty clinical research organization that focuses in the fields of study of allergy, asthma, and immunology. Red Maple Trials works with biopharmaceutical companies to deliver environmental exposure chamber studies as well as other specialty services such as clinical project management, medical support, protocol design, to name a few examples. We have a long history in clinical research and we hold ourselves to the highest standards in both quality and patient safety. Our team has delivered successfully and safely on over 240 clinical trials and we bring over 130 combined years of experience in our field.
What is a chamber study?
Chamber studies are a specialized type of environmental allergy study. They are usually done to test the safety and effectiveness of various investigational medications. The problem with most environmental allergy studies is that there is no way to know exactly how much allergen (pollen, pet dander, etc) a patient is exposed to over the course of a study. This can result in large variations in patient symptoms, and can make results and data unclear. However, in chamber studies, researchers can control exactly how much allergen patients are exposed to, making the results clearer and the data more reliable. Researchers do this by measuring the symptoms of patients in a “chamber” — a large room capable of controlling temperature, humidity and allergen concentration.
Are these studies safe?
Our team has been conducting clinical trials for over 30 years and bring a strong reputation to both our patients and our partners. Our facility was built to GMP standards and we have a stringent Code of Conduct, Good Clinical Practice (GCP) and Standard Operating Protocols that focus on patient safety, medical support, fire and emergency protocols, and ethical code of conduct. Each of our staff members is fully trained on a regular basis and we are active in ensuring both the safety and comfort of each study participant.
What is involved in participating in a study with Red Maple Trials?
This varies greatly depending on the study. In general however, studies involve patients coming in for a few appointments, where we would do various medical examinations (e.g. allergy testing, blood work, lung function testing, physical examination, etc.). Participation in a chamber study would also involve spending some time (usually 2-3 hours) in the Allergen Challenge TheatreTM or in the Naturalistic Exposure Chamber. Some studies would involve patients taking an investigational medication.
