NeoRestoration Foundation

NeoRestoration Foundation The NeoRestoration Foundation (NRF) is a 501 (c)(3) non-profit organization dedicated to funding advanced neuroscience research.

02/14/2026
02/12/2026
02/12/2026
02/12/2026
02/12/2026
02/12/2026

We’re reminded that progress isn’t always linear — and every step forward, big or small, matters. Louis’ journey after a life-altering motorcycle accident shows the power of perseverance, the importance of access to the right equipment, and what’s possible with determination and support along the way.

On his way to work, Louis was in a motorcycle accident that left him seriously injured. He sustained an incomplete spinal cord injury spanning from L1 to T10 — an injury that suddenly reshaped how he imagined his future.

Through Triumph Foundation’s Wheelchair Loaner Program, we were able to provide Louis with a chair during this critical stage of rehab. That support meant independence, mobility, and dignity at a time when everything felt uncertain.

With determination, hard work, and the right tools at the right time, Louis continued to regain strength. When he returned the wheelchair, it wasn’t because he no longer needed support — it was because he had reached a milestone many hope for and work tirelessly toward. Louis had recovered to the point where he was walking.

We’re honored to have been a small part of his recovery and proud to share his story with our community. Watch Louis' story over on our blog: https://triumph-foundation.org/news/louisstory/

02/12/2026
02/12/2026

The North American Spine Society released two documents on antithrombotic therapies for adult spine surgery patients. The publications, “Evidence-Based Clinical Guidelines for Multidisciplinary Spine Care: Antithrombotic Therapies for Adults Undergoing Spine Surgery, 2nd Edition” and “Appropri...

02/12/2026

ADHD Is a Circadian Rhythm Disorder.
Circadian rhythm dysfunction appears to be common and clinically relevant for many people with ADHD, though it is not present in everyone. A large proportion of individuals with ADHD show some form of circadian alteration, and the relationship between these disruptions and ADHD symptoms seems to run in both directions. Biological findings across studies point to consistent patterns, including delayed sleep timing, irregular melatonin and cortisol rhythms, and changes in clock gene activity, suggesting that these are not incidental findings but part of a broader physiological pattern for a substantial subgroup of patients.

At the same time, the evidence suggests a more nuanced picture than a single causal explanation. Interventions aimed at correcting circadian rhythms often improve sleep quality and can reduce core ADHD symptoms, supporting the idea that circadian disruption may contribute meaningfully to ADHD pathophysiology for some individuals. However, current research does not show that addressing circadian rhythm issues alone leads to full remission of ADHD, indicating that while circadian dysfunction may be an important factor, it is likely one piece of a more complex and multifaceted condition.

Reference: Luu B and Fabiano N (2025) ADHD as a circadian rhythm disorder: evidence and implications for chronotherapy. Frontiers in Psychiatry

11/28/2025

As part of the initiative, we're proud to offer clinical observerships at for international .

Dr. Jucilana dos Santos Viana, a who visited Barrow from the Brazilian state of Amazonas, described the observership opportunity as "a great honor."

"Unfortunately, in Amazonas, the practice of faces numerous structural limitations," she said. "So it was important to witness all the technology available at Barrow and to see that it is possible to perform quality neurosurgery with satisfactory results that significantly impact patients' quality of life."

Dr. Viana found it gratifying to observe complex procedures performed by Barrow President and CEO Michael T. Lawton, MD, and was impressed by the Institute's dedication to innovation and academic publishing.

"I would like to thank Prof. Lawton, who is one of the world leaders in the field of , for his warm welcome, for being an inspiration, and for showing that it is possible to overcome challenges and break barriers in pursuit of better neurosurgical and scientific practices," she said.

Learn more about our by visiting https://bar.rw/observers.

For people with disabilities and older adults, the constant fear of falling lingers with every step they take — cutting ...
11/16/2025

For people with disabilities and older adults, the constant fear of falling lingers with every step they take — cutting into their quality of life and affecting their independence.

Researchers at Georgia Tech have developed a smart shoe insert to better monitor foot placement for those at higher risk of falls. Designed with 3D-printed electronics, the insert offers a low-cost, less invasive option with broad implications for anyone who could benefit from the technology.

Hong Yeo, a mechanical engineering professor and director of Georgia Tech’s Wearable Intelligent Systems and Healthcare Center, led the nearly 30-person team that developed the insert with patients in mind.

“I’m not a doctor, I’m an engineer,” Yeo said. “So when it comes to developing new technologies, I always get inspiration and motivation from meeting with clinicians and physicians.”

The insert utilizes more than 170 flexible pressure sensors that measure plantar pressure in the foot, a key indicator of walking stability. With a Bluetooth connection to smartphones, the insert will allow for continuous analysis of one’s gait, enabling real world monitoring for better fall detection.

Yeo hopes this technology offers an affordable option for everyone.

In Brazil, scientists have unveiled a breakthrough drug after 25 years of research — one designed to repair spinal cord ...
11/16/2025

In Brazil, scientists have unveiled a breakthrough drug after 25 years of research — one designed to repair spinal cord injuries once thought untreatable. By activating dormant nerve pathways and encouraging new cell growth, the treatment has already shown remarkable results in early studies.

Patients in initial trials have begun regaining mobility and sensation, marking a potential turning point in the fight against paralysis. If larger trials succeed, this discovery could reshape the future of neurology and bring hope to millions worldwide who live with spinal cord damage.

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NeoRestoration Foundation

The NeoRestoration Foundation (NRF) meets a critical need for research, access and recovery in spinal cord injury treatment. Every year, around the world, between 250,000 to 500,000 people suffer a spinal cord injury (SCI). There are about 12,000 new SCIs every year, and the majority of them (82 percent) involve males between the ages of 16-30. These injuries result from motor vehicle accidents (36 percent), violence (28.9 percent) or falls (21.2 percent). A spinal cord injury (SCI) is damage to the spinal cord that causes changes in its function, either temporary or permanent. These changes translate into loss of muscle function, sensation, or autonomic function in parts of the body served by the spinal cord below the level of the lesion.

In early 2000, John Wood McDonald III, MD PhD and his team were the first to report that oligodendrocytes do regenerate when stimulated by exercise. Hence he launched new and innovative protocols known as Restorative Therapy Integration (RTI) in treating patients with spinal cord injury. This lead the way for Dr. McDonald recognizing that the micro repair of the spinal cord to restore and recover function if volitional exercise was employed. This discovery gave birth for him to develop Activity Based Restorative Therapy (ABRT).

In 2004, Dr. McDonald built and became the Executive Director of the International Center for Spinal Cord Injury ICSCI at Kennedy Krieger Institute at Johns Hopkins in Baltimore. It is here that he and his team he brought with him from St. Louis; he further expanded and improved ABRT and pushed for the expansion and improvements in technology and more research to move medical science forward. ABRT is now a therapeutic protocol used worldwide from those who have sustained a spinal cord injury and has been the driving force to expand and rewrite the protocols of treatment of people experiencing other movement disorders. The cross collaboration of world-renowned scientists from different research institutions across the world, lead to further innovations in technology, advances in stem cell treatment and improved pharmacological treatment and a better understanding of the underlying mechanisms to repair and restore muscle mass, movement and neuronal cell regeneration enabling patients to regain independence. Their plan integrates the most advanced knowledge in neuroscience, epigenetics, nanotechnology, molecular biology, electrophysiology, and functional brain imaging. According to Dr. McDonald, today, it is improvements in technology that will be the single most significant factor in moving medical science forward.

NeoRestoration Foundation was founded in 2017 by Ellizzette Duvall McDonald inspired by her brilliant husband, John W. McDonald III MD PhD, who pioneered the research and recovery in spinal cord injury patients through his stem cell research that lead to multiple other discoveries, patents and protocols in the field of neuroscience and neurology. Today his historical groundbreaking work and legacy continues among his collaborators. NRF is headquartered in New York City, with offices in St. Louis. 100% of all donations go directly to research.