03/18/2026
Evaluating the potential of acupuncture for Alzheimer’s disease treatment: A meta-analysis and systematic review of mouse model studies. From Nature.com
laboratory settings. We analyzed 29 relevant PubMed articles published between January 2014 and July 2025. Our results reveal that EA significantly reduces both amyloid-beta (Aß) and phosphorylated tau (p-tau) levels and neuroinflammatory biomarkers, including molecular signatures for activated microglia and astrocytes in the brain. EA also enhances cognitive functions. While no study directly compared acupoint strategies, the indirect comparisons in our network analysis suggest that GV20 has potential as a therapeutic target for AD. Our present meta-analysis and review of literature add to the evidence of
integrative health practices for acupuncture-based Alzheimer’s disease treatment.
Link: https://www.nature.com/articles/s41398-026-03923-9