TGen

04/10/2026

For decades, doctors and scientists used one single "reference map" to understand human DNA. The problem? That map didn't represent the incredible diversity of people all over the world.

What is Pangenomics? Instead of one map, we build a "comprehensive map" for DNA—one with hundreds of layers that show many unique paths, shortcuts, and detours in our genetic code.

Why does it matter?
Fairer Medicine: It removes "blind spots" for underrepresented populations.
Better Cancer Care: It helps us track how tumors scramble DNA.
More Accuracy: It makes your unique DNA less likely to be invisible to modern tools.

Full article below to see how the Guarracino lab is using computer engineering to build a more inclusive future for healthcare. 💻🧬

https://www.linkedin.com/pulse/pangenome-revolution-fixing-blind-spots-human-genetics-tgenresearch-hnnrc/?trackingId=RwO7JbWTSj2rX44TRGXI9A%3D%3D

People often ask what a scientist does every day – working with test tubes? Or looking at samples through a microscope? Well, we sat down with a computational scientist to learn more about his role and the research he is passionate about. TGen is excited to welcome a new faculty member, Andrea Gua...

04/09/2026

At TGen, part of City of Hope, we are looking to the DNA for an answer when it comes to patient care. 🔎

By better understanding a patient's genomic information, we aim to help healthcare providers in the treatment plan process and ultimately to improve patient care.

The Translational Genomics Research Institute (TGen) is a non-profit 501(c)(3) organization focused on developing earlier diagnostics and smarter treatments. Translational genomics research is a relatively new field employing innovative advances arising from the Human Genome Project and applying the...

04/08/2026

Science Teachers, Let’s Link Up!

The National Science Teaching Association (NSTA) conference is just around the corner, and TGen will be there. We’re excited to learn more about bringing STEM to future scientists.

Are you going to NSTA?
April 15-18
Anaheim Convention Center

Between the workshops and the exhibit hall, we invite you to connect with us –attend a session with us, grab a coffee, and chat! www.nsta.org/ana26

04/07/2026

Today is Arizona Gives Day.

At Translational Genomics Research Institute, discovery moves forward because of people—those in our labs, and those who believe in the work and choose to support it.

As part of City of Hope, we’re working together to turn research into real options for patients—faster.

Join us in moving this work forward:
https://www.azgives.org/organization/COHTGEN

04/06/2026

TBLA Applicants: Your interview is tomorrow - need help preparing?

Congrats on being selected to interview! Here are some things to remember as you prepare for the upcoming interview.

04/04/2026

Tuesday, April 7, is Arizona Gives Day.

At Translational Genomics Research Institute, discovery moves forward because of people—those in our labs, and those who believe in the work and choose to support it.

As part of City of Hope, we’re working together to turn research into real options for patients—faster.

Join us in moving this work forward:
https://www.azgives.org/organization/COHTGEN

04/03/2026

It has been said that "obesity increases cancer risk." But why?!

Scientists at City of Hope and TGen are the first to explain a major mechanism for why gaining excess weight increases your risk of cancer. Dr. Cristian Tomasetti and his team have published the first mathematical explanation in the American Association for Cancer Research (AACR): Obesity enlarges organs, increasing the total cell count that could potentially become cancerous. 📈

Math meets medicine in the latest .

Listen now: https://bit.ly/4dSs5pu

04/02/2026

Rishika’s gap year wasn't just about doing research; it was about understanding the bench-to-bedside pipeline. Through the Ivy Neurological Sciences Internship Program, she’s gained the technical and professional skills needed as a growing bioscience leader.

Learn more about the program at: https://www.tgen.org/education/the-ivy-neurological-sciences-internship-program/

03/27/2026

🌟 Celebrating the City of Hope Kindness Grant Recipients

City of Hope’s annual Kindness Grant program invests in projects that support our most vulnerable communities. The projects are led by employees in partnership with a local organization. We're proud to share that TGen had three employees who received grants, which range from $100 to $4,500, to help turn employee ideas into action.

03/26/2026

2026 marks the 20th anniversary of the partnership between TGen and Helios Education Foundation.

Dr. Joshua Niska, a 2006 alum, shares how this program laid a foundation for his work in medicine and research.