Rockefeller University Press

Rockefeller University Press RUP journals publish groundbreaking peer-reviewed research in the life sciences and biomedicine.

đź“°  : Researchers at Johns Hopkins Medicine and University of Maryland School of Pharmacy have developed a set of novel, ...
04/02/2026

📰 : Researchers at Johns Hopkins Medicine and University of Maryland School of Pharmacy have developed a set of novel, first-in-class drugs that inhibit hypoxia-inducible factors 1 and 2, a pair of transcription factors considered to be “master regulators” of cancer progression 👉 https://hubs.la/Q049gmjF0

The study, published today in the Journal of Experimental Medicine (JEM), (https://hubs.la/Q049g4fp0) shows that these drugs, when combined with immunotherapy, can completely eliminate breast, colorectal, melanoma, and prostate tumors in mice, suggesting that they could eventually be used to treat a broad range of cancers in humans.

đź“°  : Researchers in China have provided the first proof-of-principle study demonstrating that targeting a receptor on th...
04/01/2026

đź“° : Researchers in China have provided the first proof-of-principle study demonstrating that targeting a receptor on the surface of anti-inflammatory regulatory T cells (Tregs) can restore their function and alleviate in mice.
👉 https://hubs.la/Q04974x20

See the study published in Life Science Alliance: https://hubs.la/Q0497xQG0

đź“°  : Researchers at Perelman School of Medicine at the University of Pennsylvania have identified a cell surface recepto...
03/27/2026

đź“° : Researchers at Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of blood vessel abnormalities known as cerebral cavernous malformations (CCMs). The study, published today in Journal of Experimental Medicine (https://hubs.ly/Q048CkPm0), suggests that drugs targeting TIE2 could be used to prevent the formation of CCMs, which, if left untreated, can cause brain hemorrhages, strokes, and seizures. https://hubs.ly/Q048Cp0d0

Publishing in the Rockefeller University Press journals (JCB, JEM, JGP, JHI, and LSA) enables authors funded by National...
03/26/2026

Publishing in the Rockefeller University Press journals (JCB, JEM, JGP, JHI, and LSA) enables authors funded by National Institutes of Health (NIH), Howard Hughes Medical Institute (HHMI), and other funders an easy pathway to compliance. Learn more: https://hubs.la/Q048m9Jm0

This collection highlights recent JEM studies investigating the adaptive and innate immune response induced by M.   and ...
03/20/2026

This collection highlights recent JEM studies investigating the adaptive and innate immune response induced by M. and HIV-1 infection. Read new findings to accompany Keystone Symposia on Molecular and Cellular Biology meetings on and Vaccines: https://hubs.la/Q046W7rc0

JEM's new collection highlights the latest discoveries in the field of   in viral infection, barrier defense, liver heal...
03/18/2026

JEM's new collection highlights the latest discoveries in the field of in viral infection, barrier defense, liver health, inflammation, and cancer. Explore latest discoveries to accompany Keystone Symposia on Molecular and Cellular Biology on the topic:
https://hubs.la/Q046VWg50

“We have chosen to submit our work to the Journal of General Physiology because we are confident that the review process...
03/05/2026

“We have chosen to submit our work to the Journal of General Physiology because we are confident that the review process will be fair.”— Dr. Daniel Fitzsimons. Learn how scientists set the course at JGP 👉 https://hubs.la/Q045DnB30

“In my 20+ years of experience in science and research, this was one of the most constructive editorial interactions I h...
03/04/2026

“In my 20+ years of experience in science and research, this was one of the most constructive editorial interactions I have ever had… It showed me how fair and engaged editorial work grounded on competence, communication and respect can enhance the overall scientific process.”— Silvia Monticelli, Università della Svizzera Italiana, Bellinzona, Switzerland.

Discover how JEM’s collaborative model puts your science first. 👉 https://hubs.la/Q045xpnZ0

“Our goal is not simply to resolve structures, but to uncover how molecular organization shapes cellular function. Being...
03/03/2026

“Our goal is not simply to resolve structures, but to uncover how molecular organization shapes cellular function. Being highlighted by JCB affirms that this integrative approach is both valued and necessary. I’m grateful to be included in a journal with such a strong legacy in defining and advancing the field of cell biology.”— Danielle Grotjahn, Department of Integrative Structural and Computational Biology, The Scripps Research Institute.
Publish your next multidisciplinary breakthrough. Learn more about JCB’s editorial process. https://hubs.la/Q045fhxN0

JGP's March issue is here! https://hubs.la/Q045b9Wn0 Subthreshold current pulses delivered to pairs of electrically coup...
03/02/2026

JGP's March issue is here! https://hubs.la/Q045b9Wn0
Subthreshold current pulses delivered to pairs of electrically coupled MesV neurons w/ systematically varied inter-pulse delays reveal that electrical synapses enable coincidence detection (Dapino & Curti https://hubs.la/Q045bgY50).

Our March issue is here! https://hubs.la/Q045bgg70The cover depicts fluorescent immunohistochemistry staining of a human...
03/02/2026

Our March issue is here! https://hubs.la/Q045bgg70
The cover depicts fluorescent immunohistochemistry staining of a human lung granuloma: (yellow), SPP1+ cells (green), macrophages enriched in alveolar spaces (red), and nuclei (blue). See Mbano et al. https://hubs.la/Q045bfYz0

JCB's March cover (https://hubs.la/Q045bf5R0) is an immunofluorescence image of nurse cells in the   o***y.   cables (cy...
03/02/2026

JCB's March cover (https://hubs.la/Q045bf5R0) is an immunofluorescence image of nurse cells in the o***y. cables (cyan) assembling at the nurse cell cortex co-align w/ acetylated (magenta) as they grow toward the nuclei. See Chou et al. https://hubs.la/Q045b5Yw0

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